• <nav id="qoigg"></nav>
      設為主頁 加入收藏 English


    發布時間:2020-12-26  點擊次數:92  新聞來源:

      文獻名: Second Near-Infrared Aggregation-Induced Emission Fluorophores with Phenothiazine Derivatives as the Donor and 6,7-Diphenyl-[1,2,5]Thiadiazolo[3,4-g]Quinoxaline as the Acceptor for In Vivo Imaging


    作者: Shun Li, Changfeng Yin, Ruonan Wang, Quli Fan, Wei Wu*, and Xiqun Jiang

    Department of Polymer Science and Engineering, College of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, P. R. China


    摘要:Traditional organic fluorophores generally have hydrophobic conjugated backbones and exhibit an aggregation-caused quenching emission property, which limits greatly their applications in the biological field. Aggregation-induced emission (AIE) fluorophores can breakthrough this shortcoming and are more promising in biological imaging. In this paper, we synthesized three novel donor–acceptor–donor-type second near-infrared (NIR-II) fluorophores and studied their geometric and electronic structures and photophysical properties by both theoretical and experimental studies. All the three fluorophores had typical AIE characteristics, and their emission wavelength spanned the traditional near-infrared and NIR-II regions. They exhibited much stronger fluorescence after being encapsulated in polymer nanoparticles (NPs) than in solutions, and the fluorophore-loaded NPs had desirable biosafety and significant tumor accumulation, indicating that they have great application potentials in tumor detection.

    上海市普陀區嵐皋路567號1108-26室 電話:021-62665073 400-718-7758 傳真:021-62761957
    美國布魯克海文儀器公司上海代表處 版權所有  管理登陸 備案號:滬ICP備19006074號-1 技術支持:化工儀器網